Abiraterone
- Catalog NO.:A24884
- CAS No. : 154229-19-3
- Molecular Formula:C24H31NO
- Molecular Weight: 349.51
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Product Details
CAS Number | 154229-19-3 | Appearance | White powder |
Catalog Number | A24884 | MDL Number | MFCD00924100 |
Molecular Formula | C24H31NO | Molecular Weight | 349.51 |
Boiling Point | 500°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | CB-7598;17-(3-Pyridyl)androsta-5,16-dien-3beta-ol | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H332-H335 | Class | |
Precautionary Statements | P261-P280-P305+P351+P338 | Packing Group |
Description
Abiraterone, also known as CB7598, is the active metabolite of abiraterone acetate, which is an orally active acetate ester of the steroidal compound abiraterone with antiandrogen activity. Abiraterone acetate was approved by the U.S. Food and Drug Administration (FDA) in April 2011. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. |